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Botox is a neurotoxic protein produced by the bacterium Clostridium botulinum and it can be used for medical and cosmetic purposes. Botox is safe and effective in reducing facial wrinkles, especially in the uppermost third of the face. Botox can also be used to relax clenching of jaw muscles. Patients who have temporal mandibular joint problem/myofascial pain related to muscle clenching may obtain relief after Botox injection.